Mohammad Ali Hosseinian; Tooraj Salimi
Abstract
Background: Fibrin glue can be used for nerve repair. This study is to evaluate the repair of severed sciatic nerve in rats done by fibrin glue, comparing with an untreated group. Methods: In an interventional case series study, 18 Sprague rats had their sciatic nerve cut in the intervertebral canal. ...
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Background: Fibrin glue can be used for nerve repair. This study is to evaluate the repair of severed sciatic nerve in rats done by fibrin glue, comparing with an untreated group. Methods: In an interventional case series study, 18 Sprague rats had their sciatic nerve cut in the intervertebral canal. Fourteen rats were repaired by graft-repairing of nerve using fibrin glue and single suture. Four rats were left untreated as controls. The recovery of motor function was assessed after 4 months. Results: Lower extremity muscle atrophy and absence of motor function recovery was observed in the untreated rats. Full functional recovery in lower limbs was observed in the 12 treated rats, while 2 rats walked with limp. Conclusion: The cut sciatic nerve repair in rat's spinal canal, using fibrin glue and a microsurgical suture would result in good function motor recovery of lower extremity.
Mohammad Ali Hosseinian, MD; Tooraj Salimi, MD; Yalda Soleimanifard, MD; Kourosh Sheibani, MD
Abstract
Background: Thoracic oulet syndrome is treated using non-surgical or surgical approaches. Surgical treatment is necessary if non-surgical treatments fail. In this study we compared the supraclavicular and transaxillary approaches for surgery of the brachial plexus.Methods: We, retrospectively, studied ...
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Background: Thoracic oulet syndrome is treated using non-surgical or surgical approaches. Surgical treatment is necessary if non-surgical treatments fail. In this study we compared the supraclavicular and transaxillary approaches for surgery of the brachial plexus.Methods: We, retrospectively, studied 69 patients undergoing surgery to treat thoracic outlet syndrome from 2001 to 2008. Twenty six patients had bilateral thoracic outlet syndrome. Sixty three cases were operated with supraclavicular approach for the first time, 32 cases were operated with transaxillary approach for the first time, and 7 cases were reoperated with supraclavicular approach. The complications were evaluated for 24 months.Results: Pneumothorax, hemothorax, vessels injury in transaxillary and supraclavicular approach were the same but permanent and transient brachial plexus injury in transaxillay approach were more than supraclavicular approach.Conclusion: Supraclavicular approach for surgical treatment of thoracic outlet syndrome provides better access to braxial plexus and there is less need for reoperation compared to transaxillary method.